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. 2011 Dec 9;3(2):96–104. doi: 10.1021/cn200083m

Figure 1.

Figure 1

Effects of the biogenic amines on GABA-currents in oocytes expressing GABAρ1 receptors. (A) Effect of biogenic amines at several concentrations upon currents activated by 3.5 μM GABA. (B) Monoamine concentration–response relationships showing the IC50 for each one. Data were normalized to the maximal GABA response (3.5 μM) of each oocyte (C) DA and 5-HT did not modulate GABA-A receptors. DA (■), 5-HT (●), Tyra (▲), and Octo (▼). Data points are the means ± SEM obtained from at least 9 oocytes (n = 9) from 5 different frogs (N = 5).