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. 2011 Dec 9;3(2):96–104. doi: 10.1021/cn200083m

Figure 4.

Figure 4

Effect of the GABAρ receptor antagonist TPMPA on the GABA-elicited currents modulated by DA. (A) Sample records showing that TPMPA effectively and reversibly blocked the currents generated by 3.5 μM GABA and those modulated by 105, 210, and 750 μM DA. Note that the coapplication of DA concentration, higher than 105 μM, and TPMPA enhanced the inhibitory effect. (B) TPMPA antagonism on currents elicited by coapplication of GABA and either DA at 105, 210, and 750 μM. Data points are the means ± SEM from 6 oocytes (n = 6) from 5 frogs (N = 3).