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. 2011 Dec 9;3(2):96–104. doi: 10.1021/cn200083m

Figure 5.

Figure 5

Effect of the GABAρ receptor antagonist TPMPA on the GABA-elicited currents modulated by 5-HT. (A) Sample records showing that TPMPA effectively and reversibly blocked the currents generated by 3.5 μM GABA and modulated by 175, 340, and 900 μM 5-HT. (B) TPMPA antagonism on currents elicited by coapplication of GABA and either 5-HT at 175, 340, and 900 μM. The currents were adjusted to the amplitude the maximum current for each curve. Data points are the means ± SEM from 6 oocytes (n = 6) from 5 frogs (N = 5).