Table 1. The effect of GAS (300 µM) on active membrane properties of capsaicin-sensitive DRG neurons.
n | APAmplitude(mV) | APhalf-width(ms) | APmax-rise slope(mV/ms) | APmax-decay slope(mV/ms) | APthreshold(mV) | |
Control | 30 | 98.57±2.94 | 2.77±0.21 | 96.18±5.37 | –87.45±5.14 | –26.67±2.29 |
Control + GAS | 6 | 98.46±4. 71 | 2.83±0.44 | 96.41±7.91 | –98.73±11.41 | –22.48±4.56 |
Diabetic | 35 | 115.39±3.29 * | 2.01±0.18 * | 124.23±11.55 * | –72.32±8.43 * | –37.39±2.68 * |
Diabetic + GAS | 25 | 92.32±2.85 # | 2.36±0.20 | 98.77±5.21 # | –98.52±6.54 # | –22.56±2.32 # |
represents significant difference between control and diabetes.
represents significant difference between GAS and diabetes.