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. 2012 Jun 25;7(6):e39770. doi: 10.1371/journal.pone.0039770

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Gan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Grg4 transcripts were significantly elevated following TSA (left) and VPA (right) treatments in dose and time-dependent manners using real-time PCR analysis in GT1–7 cells. Values for control samples were set as 1.0. (n = 3). (B) The total protein levels and (C) nuclear protein levels of Grg4 in GT1–7 cells 24 h after HDACIs treatments were determined by western blot.