Table 1. IC50 values (µM) of thalidomide derivatives for inhibiting proliferation of multiple myeloma cell lines.
Cell line | Compound | |||||||||
TC8 | TC9 | TC10 | TC11 | TC12 | TC13 | TC14 | TC15 | TC16 | Thalidomide | |
KMM1 | >50 | >50 | >50 | 7 | 18 | 5 | 32 | >50 | >50 | >50 |
KMM11 | >50 | >50 | >50 | 6 | 14 | 4 | 7 | >50 | >50 | >50 |
KMS27 | >50 | >50 | >50 | 8 | 25 | 8 | 34 | >50 | >50 | >50 |
KMS34 | >50 | >50 | 25 | 4 | 16 | 5 | 14 | >50 | >50 | >50 |
RPMI8226 | >50 | >50 | >50 | 7 | 26 | 11 | 24 | >50 | >50 | >50 |