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. 2004 Feb 15;113(4):591–597. doi: 10.1172/JCI19557

Figure 1.

Figure 1

(a–f) Representative histological sections of small intestine in indomethacin-treated mice. Immunohistology of control WT (a) and Vanin-1–/– (b) mice using anti–Vanin-1 mAb labeling. Cross and longitudinal intestinal sections from WT (c and e) and Vanin-1–/– (d and f) mice; arrows, swollen intestinal villi and dilated lymphatic channels. Hematoxylin-phloxine-saffron staining. Magnification: ×160 (a and b), ×40 (c and d), and ×100 (e and f). (g) Lower intestinal MPO activity in indomethacin-treated WT and Vanin-1–/– mice (white bars, control; black bars, treated). Values are means ± SD. Values from Vanin-1–/– and WT groups are significantly different (P < 0.05, Student t test).