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Relative risk of colorectal cancer occurrence in a proband associated with different constellations of family history[33]
| No. of FDRs with CRC | No. of SDRs with CRC | No. of TDRs with CRC | Relative risk (95% CI) |
| 1 | 0 | 0 | 1.76 (1.63-1.89) |
| 2 | - | - | 3.01 (2.66-3.38) |
| 0 | 2 | - | 1.20 (1.05-1.38) |
| 1 | 1 | - | 2.12 (1.90-2.35) |
| 1 | 2 | - | 2.31 (1.80-2.93) |
| 0 | 1 | 2 | 1.33 (1.13-1.55) |
FDR: First-degree relative; SDR: Second- degree relative; TDR: Third- degree relative; CI: Confidence interval; CRC: Colorectal cancer.
