Skip to main content
. 2012 Jun 15;4(6):145–151. doi: 10.4251/wjgo.v4.i6.145

Table 2.

The area under the receiver operating characteristic curve and 95% confidence interval of serum pyruvate kinase isoenzyme M2 in U/mL and carcinoembryonic antigen in ng/mL in diagnosing colorectal lesions in colorectal cancer mass screening in Hangzhou, China, 2006-2008

Colorectal lesion Test AUC SE P-value 95% CI
CRC stage I and II CEA 0.70 0.04  < 0.0001 0.62-0.79
M2-PK 0.89 0.03  < 0.0001 0.84-0.94
CRC stage III CEA 0.73 0.05  < 0.0001 0.63-0.83
M2-PK 0.89 0.03  < 0.0001 0.84-0.94
Advanced adenoma CEA 0.63 0.05 0.01 0.53-0.73
M2-PK 0.81 0.04  < 0.0001 0.74-0.86
Adenoma CEA 0.54 0.03 0.28 0.47-0.60
M2-PK 0.69 0.03  < 0.0001 0.64-0.76
Nonadenomatous polyp CEA 0.58 0.05 0.09 0.48-0.68
M2-PK 0.69 0.04  < 0.0001 0.62-0.78
Inflammatory bowel disease CEA 0.41 0.10 0.40 0.21-0.61
M2-PK 0.42 0.10 0.40 0.21-0.63

AUC: Area under the receiver operating characteristic curve; CRC: Colorectal cancer; CI: Confidence interval; M2-PK: M2-pyruvate kinase; CEA: Carcinoembryonic antigen.