Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jul;140(1):69–82. doi: 10.1085/jgp.201210776

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 Brauser et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 6. — Examples for fitting of amplitude histograms in the presence of 0.3 mM enrofloxacin on the cis side in an LPS membrane. Data are taken from Fig. 4 B. (A) Successful fitting of Gaussians (red) to an all-point amplitude histogram with slow blocking measured at −100 mV resulting in σ₀ = 2.6 pA and an estimated single-pore current I_app = 20.8 pA. (B) Failure of fitting an open-point histogram measured at +100 mV by a Gaussian distribution (blue dotted line). Successful fitting of the data with a β distribution (red solid line) resulting in I_true = 22.7 pA, I_B = 12 pA, k_OB = 20 700 s^-1, and k_BO = 67 000 s^-1 (Eq. 1, Figs. 1 C and 5).