Table 1.
Stage dependent marker expression for the astroglial differentiation lineage.
| Marker | Early precursor cell | Late precursor cell | Astrocyte precursor | Mature astrocyte | Citations |
|---|---|---|---|---|---|
| Nestin | + | + | − | − | Rauch et al. (1997), Kornblum et al. (1998) |
| BLBP | + | + | − | − | Rauch et al. (1997), Kornblum et al. (1998) |
| FGFR | + | + | − | − | Kornblum et al. (1998) |
| GLAST | − | + | + | + | Lehre et al. (1995) |
| EGFR | − | + | +? | − | Karus et al. (2011) |
| Tnc | − | + | + | − | Lehre et al. (1995), Karus et al. (2011) |
| FGFR3 | − | − | + | + | Cahoy et al. (2008) |
| S100β | − | − | + | + | Nagelhus et al. (2004) |
| Aqp4 | − | − | + | + | Nagelhus et al. (2004) |
| AldH1L1 | − | − | + | + | Cahoy et al. (2008) |
| GFAP | − | − | − | + | Meeuwsen et al. (2003) |
BLBP, basic lipid binding protein; FGFR/FGFR3, Fibroblast growth factor receptor (3); GLAST, Glutamate-Aspartate Transporter; EGFR, Epidermal growth factor receptor; Tnc, Tenascin C; Aqp4, Aquaporin 4; AldH1L1, Aldehyde dehydrogenase 1, member L1; GFAP, Glial fibrillary acidic protein.