Figure 2.

Effect of selenium on the formation of gastric lesions after oral administration of ethanol to rats. A vehicle (selenium, 0 μg/kg) and three doses (10, 50, and 100 μg/kg of body weight) of selenium were given as pretreatment for 3 days, and then gastric mucosal damage was induced by 80% ethanol treatment for 3 days. Selenium pretreatment significantly attenuated the gastric damage area in the stomach in a dose dependent manner, compared with 80% ethanol alone. Values are expressed as the mean ± SEM. ^* p < 0.05, significantly different from the untreated normal rats; ^** p < 0.01, significantly different from the control rats.