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. 2012 May 11;13(5):5740–5750. doi: 10.3390/ijms13055740

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© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

PMC Copyright notice

An immediate gastroprotective effect of selenium on ethanol-induced gastric lesions in rats. One hundred μg/kg selenium was given as pretreatment for 3 days, and then gastric mucosal damage was induced by 80% ethanol treatment for 3 days. (A) Gastric ulcer in ethanol-treated rat; (B) Gastric mucosa in selenium-pretreated rat. 100 μg/kg selenium prevents ethanol-induced gastric lesions by direct protection of gastric mucosa.