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. 2012 May 11;13(5):5740–5750. doi: 10.3390/ijms13055740

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© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Effect of selenium against lipid peroxidation in gastric mucosa. The rats were pretreated with a vehicle (selenium, 0 μg/kg) and three doses (10, 50, and 100 μg/kg of body weight) of selenium for 3 days, and then gastric mucosal damage was induced by 80% ethanol treatment for 3 days. Malonylaldehyde (MDA) production was estimated by using a thiobarbituric acid reaction. Selenium pretreatment reduced the level of MDA in a dose dependent manner in comparison to the control group. Values are expressed as the mean ± SEM. ^* p < 0.05, significantly different from the untreated normal rats; ^** p < 0.01, significantly different from the control rats.