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. 2012 Jul;40(7):1321–1327. doi: 10.1124/dmd.111.043752

TABLE 2.

Summary table for modeled clearance values

Clearances are expressed as l · h−1 · kg−1.

UGT1A9 Clearance
Parameter Well Stirred
Parallel Tube
Allometric Simcyp Allometric Simcyp
Normalized adult clearance 1.1 1.2
r2 0.7 0.8
95% CI of adult clearance 1.0, 1.3 Did not converge 1.1, 1.4 Did not converge
Age at adult activity 17.9 yr 19.5 yr
Absolute sum of squares 4.8 4.4
Sy.x 0.19 0.18