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. 2012 Jul;130(1):e115–e125. doi: 10.1542/peds.2011-3693

TABLE 4.

Models Using Variables at 7 DAYS of Age (n = 6996)

Variable Time Period When Variable Was Evaluated AUC c-statistic % Increase in AUC OR (95% CI) P
Death/NDI
 Birth weight, g Birth 0.659 0.71 (0.68–0.74) (per 100-g increase) <.0001
 Highest Fio2 on day 7 Day 7 0.690 3.1 1.18 (1.14–1.21) (per 10% increase) <.0001
 Male gender Birth 0.708 1.8 1.88 (1.69–2.10) <.0001
 IVH grade (diagnosis by day 7) Day 7 0.717 0.9 4.40 (3.04–6.39) grade IV <.0001
1.91 (1.33–2.74) grade III
 Days on CPAP (to day 7) Day 7 0.724 0.7 0.89 (0.86–0.92) (per 1 d more) <.0001
Death before discharge
 Highest Fio2 on day 7 Day 7 0.716 1.28 (1.24–1.32) <.0001
 Birth weight, g Birth 0.760 4.4 0.62 (0.59-0.65) <.0001
 IVH grade (diagnosis by day 7) Day 7 0.770 1.0 3.55 (2.65–4.75) grade IV <.0001
1.89 (1.31–2.74) grade III
 Male gender Birth 0.774 0.4 1.61 (1.40–1.86) <.0001
NDI in survivors
 Birth weight, g Birth 0.606 0.82 (0.78–0.86) <.0001
 Male gender Birth 0.639 3.3 1.76 (1.56–2.00) <.0001
 Days on CPAP (to day 7) Day 7 0.655 1.6 0.98 (0.93-1.02) (per 1 d more) .2720
 Apgar score at 5 min Birth 0.662 0.7 0.93 (0.90–0.96) (per point increase) <.0001
 Days on HFV (to day 7) Day 7 0.667 0.5 1.20 (1.14–1.26) (per 1 d more) <.0001
 Days on CV (to day 7) Day 7 0.676 0.8 1.11 (1.07–1.14) (per 1 d more) <.0001

CI, confidence interval; CV, conventional ventilator; HFV, high-frequency ventilator; OR, odds ratio.