Table 1.
Phase 1 Treatment | Regr. | No Regr. | Phase 2 Treatment | Regr. | No Regr. | Chi-Square Test | |
---|---|---|---|---|---|---|---|
Experiment 1 | 16L | 0 | 20a | 10L | 10 | 16b | Control |
LL | 22 | 24c | 10L | 2 | 20 | p < 0.05 | |
Experiment 2 | 16L | 0 | 14 | 10L | 6 | 8 | Control |
10L | 9 | 1c | 10L | 0 | 9 | p < 0.05 | |
Experiment 3 | 16L | 0 | 34 | Pinx in 16L | 8 | 14 | Control |
Sham in 16L | 0 | 12 | p < 0.05 | ||||
10L | 29 | 6c | Pinx in 10L | 0 | 17 | p < 0.01 | |
Sham in 10L | 1 | 11 | |||||
Experiment 4 | 16L | 0 | 11 | LL | 5 | 6 | Control |
10L | 12d | 2d | LL | 0 | 9 | p < 0.02 |
ETV was not measured for 7 hamsters in phase 1.
One hamster died after 4 weeks of phase 2.
Nonresponders were removed from phase 2 analyses.
Three responders and 2 nonresponders were removed for a separate experiment before phase 2.