Table 2.
Antiproliferative effect of pyrroline mixtures.
| mixture | % cell viabilitya
|
|
|---|---|---|
| HeLa | MCF-7AZ | |
| ct -1 | 81 ± 4 | 72 ± 2 |
| ct -2 | 97 ± 1 | 80 ± 4 |
| ct -3 | 70 ± 2 | 45 ± 4 |
| ct -4 | 72 ± 2 | 50 ± 4 |
| ct -5 | 86 ± 3 | 61 ± 3 |
| ct -6 | 103 ± 3 | 93 ± 2 |
| ct -7 | 65 ± 1 | 58 ± 4 |
| ct -8 | 91 ± 4 | 72 ±3 |
| ct -9 | 108 ± 4 | 97 ± 4 |
| ct -10 | 69 ± 1 | 45 ± 1 |
| ct -11 | 65 ± 2 | 54 ± 2 |
| ct -12 | 105 ± 1 | 72 ± 3 |
| ct -13 | 36 ± 1 | 50 ± 2 |
| ct -14 | 98 ± 2 | 69 ± 4 |
| ct -15 | 115 ± 2 | 90 ± 4 |
| ct -16 | 79 ± 1 | 45 ± 3 |
| ct -17 | 84 ± 2 | 57 ± 4 |
| ct -18 | 104 ± 2 | 78 ± 2 |
| ct -19 | 54 ± 1 | 38 ± 2 |
| ct -20 | 46 ± 1 | 27 ± 1 |
| ct -21 | 107 ± 2 | 90 ± 4 |
| ct -22 | 102 ± 3 | 81 ± 2 |
| ct -23 | 49 ± 3 | 58 ± 2 |
| ct -24 | 102 ± 4 | 72 ± 2 |
| ct -25 | 45 ± 3 | 35 ± 3 |
| ct -26 | 36 ± 1 | 54 ± 2 |
| ct -27 | 45 ± 3 | 31 ± 2 |
| ct -28 | 82 ± 4 | 73 ± 2 |
| ct -29 | 98 ± 1 | 80 ± 4 |
| ct -30 | 82 ± 4 | 73 ± 2 |
a
% Remaining cell viability after 48 h of treatment with indicated pyrroline mixtures at the final concentrations of 100 μM relative to DMSO control. The data are mean ± SD of two independent experiments, each performed in 4 replicates, determined by MTT assay.