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. Author manuscript; available in PMC: 2012 Jun 26.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Jan 11;18(4):1392–1396. doi: 10.1016/j.bmcl.2008.01.019

Table 3.

Apoptosis inducing and cell killing properties of pyrroline c-25.

compound % apoptosisa % live cellsb
c-25 (50 μM) 30 ± 2 56 ± 4
t-25 (50 μM) 3 ± 1 96 ± 3
podophyllotoxin (5 μM) 63 ± 2 22 ± 1
a

% Apoptotic Jurkat cells after 48 h of treatment with indicated compounds relative to DMSO control.

b

% Live Jurkat cells after 48 h of treatment with indicated compounds relative to DMSO control. The data are mean ± SD of two independent experiments, each performed in 3 replicates, determined by flow cytometric Annexin-V/propidium iodide assay.