Table 1.
Relative potency of antagonists
| Antagonist | IC50, μM |
||
|---|---|---|---|
| Tetramer | ULC formation | Activation | |
| PF4A01 | 20 | 59 | 33 |
| PF4A17 | ND | ND | ND |
| PF4A31-01 | 72 | 200 | 440 |
| PF4A31-04 | 81 | 190 | 100 |
| PF4A35 | 500 | 1300 | 500 |
ND indicates not detectable.
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