Table 3.

Toxicities: grade 3 or greater nonhematologic toxicities regardless of attribution during cycles 1-2

Infections/febrile neutropenia	11 patients
Pneumonia	4
Cellulitis	1
Bloodstream	2
Neutropenic fever	4
Organ toxicities*	23 events
Neurotoxicity	3
Gastrointestinal	3
Pulmonary	3
DVT/PE	2
Hyperglycemia	6
Confusion	1
Rash	1
Acute renal failure	1
Atrial fibrillation	1
Syncope	2
Death	4 patients
Infection	2
Pulmonary fibrosis	1
Disease	1

DVT indicates deep-vein thrombosis; and PE, pulmonary embolism.

^*Toxicities that recurred in individual patients in both cycles 1 and 2 are listed as 2 events.