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SETBP1 activation is involved in human CML progression. Real-time RT-PCR analysis of SETBP1, HOXA9, and HOXA10 mRNA levels in total RNA isolated from whole BM of healthy volunteers (normal) and CML chronic phase (CML CP) and advanced/blast crisis phase (CML AP/BC) patients (*samples expressing high SETBP1 mRNA levels). Relative expression levels were calculated by normalizing to BCR mRNA levels in the same sample.
