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Comparative killing ability of TG versus its analogues against a series of human prostate cancer cell lines
| Cell line | Killing ability of compound | ||||
|---|---|---|---|---|---|
| (LD50 nmol/L)* | |||||
| TG | 12ADT | A12ADT | L12ADT | D12ADT | |
| LNCaP | 10 ± 5 | 55 ± 12 | 8 ± 4 | 14 ± 8 | 40 ± 12 |
| LAPC-4 | 25 ± 6 | 80 ± 19 | 28 ± 7 | 32 ± 9 | 55 ± 9 |
| VCaP | 20 ± 7 | 67 ± 25 | 23 ± 9 | 25 ± 11 | 70 ± 18 |
| MDA-PC-2b | 43 ± 12 | 95 ± 35 | 40 ± 6 | 42 ± 5 | 51 ± 12 |
| CWR22Rv1 | 38 ± 9 | 85 ± 27 | 38 ± 11 | 34 ± 16 | 39 ± 7 |
Values are the mean of a minimum of three independent experiments ± SE.
