Table 2.

Demographic/Therapeutic Characteristics and Risk of Cardiomyopathy

Characteristic	Odds Ratio*	95% CI	P
Sex
Male	1.0
Female	1.47	0.9 to 2.4	.13
Age at primary cancer diagnosis, per year increase	0.99	0.93 to 1.04	.59
Chest radiation
No	1.0
Yes	4.29	1.9 to 9.6	< .001
Cumulative anthracycline exposure, mg/m2			< .001†
0	1.0
1-100	1.65‡	0.5 to 5.6
101-150	3.85	1.1 to 13.9
151-200	3.69	1.0 to 13.6
201-250	7.23	2.3 to 22.5
251-300	23.47	7.4 to 74.2
≥ 301	27.59	9.3 to 82.1

^*Odds ratios were obtained using multivariate conditional logistic regression.

^†P for trend.

^‡Association between anthracycline exposure at 1 to 100 mg/m² and cardiomyopathy is not statistically significant.