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. 2012 Apr 23;30(15):1842–1848. doi: 10.1200/JCO.2011.37.9990

Table 4.

EFS and OS of Patients With INSS Stage 2a and 2b Disease

Characteristic No. of Patients
EFS
OS
Stage 2a Stage 2b Stage 2a
Stage 2b
P Stage 2a
Stage 2b
5-Year EFS (%) ± SE (%) 5-Year EFS (%) ± SE (%) 5-Year OS (%) ± SE (%) 5-Year OS (%) ± SE (%)
Age, months .2837 .0037
    < 18 83 155 92 4 88 3 99 2 99 1
    ≥ 18 62 82 94 4 80 5 97 3 90 4
MYCN status
    Not amplified 144 236 92 3 85 3 98 2 96 2
    Amplified 1 0 No event NA No death NA
    Unknown 0 1
Histology .0023 < .001
    Favorable 115 170 91 3 90 3 98 2 99 1
    Unfavorable 30 64 97 4 72 7 96 4 86 5
    Unknown 0 3
Ploidy .0129 < .001
    Hyperdiploid 103 171 92 3 89 3 98 2 99 1
    Diploid 34 53 91 6 75 8 97 4 84 6
    Unknown 8 13

Abbreviation: EFS, event-free survival; NA, not applicable to this low-risk study; OS, overall survival.