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. 2012 May 17;119(26):6344–6353. doi: 10.1182/blood-2011-03-342055

Figure 5.

Figure 5

CD62L T cells are activated on transfer into allogeneic recipients. Bulk, CD62L+, or CD62L T cells (1 × 106) from unprimed B6 CD45.1 mice were transplanted into lethally irradiated BALB/c recipients. On day 6, splenocytes were harvested and stained with indicated antibodies for flow cytometry analysis. The data shown including histogram, percentage of positive cells, mean fluorescence intensity (MFI), and total positive cells were gated on CD45.1+ T cells (all transplanted donor T cells). Normal B6 CD45.1 mice were included as a control. Each group contained 5 to 8 mice. The data are the representative of 2 independent experiments. All values represent means + SD (A) CD4+ T cells. (B) CD8+ T cells (*P < .05, CD62L vs B6 CD45.1; #P < .05, CD62L vs bulk; &P < .05, CD62L vs CD62L+).