Tab 2.
Apparent permeability coefficient (Papp) values and transport-enhancement ratio (R) values for atenolol transport across excised rat intestinal tissue in the absence and presence of the selected aloe materials
| Experimental group | Papp × 10–6 (cm/s) at pH 7.4 | R |
|---|---|---|
| AFG | 0.81 ± 0.07 | 0.70 |
| AFP | 0.84 ± 0.32 | 0.73 |
| AFWL | 0.78 ± 0.03 | 0.67 |
| AVG | 1.24 ± 0.10 | 1.07 |
| AVWL | 0.81 ± 0.23 | 0.70 |
| DMG | 0.94 ± 0.34 | 0.81 |
| DMGP | 2.14 ± 0.33# | 1.84 |
| DMWL | 0.74 ± 0.18 | 0.64 |
| DMWLP | 2.06 ± 0.73 | 1.78 |
| Control (atenolol alone) | 1.16 ± 0.27 | 1.00 |
| Positive control (SLS) | 2.13 ± 0.06# | 1.84 |
AVG = Aloe vera gel; AVWL = Aloe vera whole leaf; AFG = Aloe ferox gel;
AFWL = Aloe ferox whole leaf; AFP = Aloe ferox polysaccharide;
DMG = Daltonmax700® gel; DMWL = Daltonmax700® whole leaf;
DMGP = Daltonmax700® gel precipitated polysaccharides;
DMWLP = Daltonmax700® whole leaf precipitated polysaccharides.
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Statistically significantly different from the control group (atenolol alone).