. Author manuscript; available in PMC: 2012 Jun 26.

Published in final edited form as: J Med Chem. 2006 Nov 16;49(23):6789–6801. doi: 10.1021/jm0608356

Table 2.

The matrix of cross-enrichments. The color-coded table unit presents poor (white), medium (green), good (red) and very good enrichment (black). Dark boxes are drawn around related targets (Nuclear hormone receptors, kinases, serine proteases, metallo-enzymes, folate enzymes, and other enzymes).

graphic file with name nihms380794t1.jpg

Very good (ET_max ≥ 30 and ET₂₀ ≥ 3), good (30 > ET_max ≥ 20 and 3 > ET₂₀ ≥ 2.5), medium (20 > ET_max ≥ 10 and 2.5 > ET₂₀ ≥ 2) and poor (ET_max < 10 and ET₂₀ < 2). The only exception is when one of the two enrichment indicators is well above the defined cutoff while the other is marginally below the defined cutoff, and then an averaged enrichment performance is assigned to compensate it.