Table 5.
Significant genes in the overall analysis of the 5 line-pairs associated with certain pathways identified by Ingenuity Pathway Analysis or KEGG
Biological System | Genes with higher expressiona | Genes with lower expressionb |
---|---|---|
Dopamine | 8 genes: Adcy9, Comt, Ppp1r12c, Ppm1b, Ppp2r5b, Ppp2r5c, Ppp4r1, Qdpr | 3 genes: Prkar2a, Ppp2r1b, Ppp3r1 |
Glutamatergic synapse | 9 genes: Adcy9, Glul, Gls, Gnas, Gng13, Gng3, Slc38a1, Slc38a2, Slc38a3 | 4 genes: Homer2, Pla2g12a, Pld2, Ppp3r1 |
GABA | 1 gene: Abat | 1 gene: Aldh9a1 |
Genes with higher expression in high vs. low ethanol consuming lines.
Genes with lower expression in high vs. low ethanol consuming lines.