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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Dec 8;1819(9-10):1080–1087. doi: 10.1016/j.bbagrm.2011.11.008

Figure 5. Potential physiological roles of the AAA+ proteases in mtDNA function.

Figure 5

The model shows that the three AAA+ proteases in the mitochondrial matrix regulate mitochondrial protein levels to sustain proper mtDNA functions, such as mtDNA packaging and stability, replication, transcription and translation.