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. Author manuscript; available in PMC: 2013 Aug 16.
Published in final edited form as: Neuroscience. 2012 Apr 30;217:56–66. doi: 10.1016/j.neuroscience.2012.04.054

Figure 3. The soluble C-terminus of Kv2.2 displaces full-length Kv2.1 from cell-surface clusters but does not affect the steady-state voltage-dependence of Kv2.1.

Figure 3

A. Representative maximum intensity projections of cultured hippocampal neurons expressing either full-length GFP-Kv2.1 only (left) or GFP-Kv2.1 + Kv2.2CT (right). B. Maximum intensity projections of either GFP-Kv2.1 only (left) or GFP-Kv2.1 + Kv2.2CT (right) expressed in HEK293 cells. C. Representative whole-cell recordings from HEK293 cells expressing either full-length GFP-Kv2.1 (left) or GFP-Kv2.1 + Kv2.2CT (right). Scale bars: 50 ms, 1 nA. D. Average normalized I-V relationships for full-length Kv2.1 and Kv2.1 + Kv2.2CT.