Least squares mean changes from baseline in pain scores. From Study 2 (placebo, n=401; milnacipran 100 mg/day, n=399; milnacipran 200 mg/day, n=396) [data on file], observed cases. *p<0.05; **p <0.01; ***p<0.001 versus placebo; PED, patient experience diary; VAS, visual analog scale.