Table 2.
Oxidative stress and inflammatory markers in healthy controls and nonsupplemented osteoarthritis subjects (mean ± SD).
| Subject number | Particulars | Control group (n = 40) | Group I (n = 40) | Percentage increase | Percentage decrease |
|---|---|---|---|---|---|
| 1 | SOD level (U/g Hb) | 1547.41 ± 14.72 | 1064.75** ± 20.03 | — | 31.2 |
| 2 | Ceruloplasmin (mg%) | 25.3 ± 1.69 | 30.57 ± 1.02* | 21.7 | — |
| 3 | GSHPx (IU/g Hb) | 28.70 ± 2.37 | 20.59 ± 1.36* | — | 28.5 |
| 4 | Catalase (KU/L) | 32.87 ± 1.70 | 21.87 ± 1.62** | — | 33.6 |
| 5 | Malondialdehyde (µmol MDA/ml) | 2.73 ± 0.18 | 3.81 ± 0.21** | 39.2 | — |
| 6 | CRP (mg/L) | 3.37 (0.15) | 5.32 (0.14)** | 57.8 | — |
| 7 | IL-6 (pg/ml) | 47.5 (1.3) | 73.0 (4.9)** | 53.6 | — |
*
p < 0.05, significant; **p < 0.001, highly significant.
SOD, superoxide dismutase; GSHPx, glutathione peroxidase; CRP, plasma C- reactive protein; IL-6, synovial interleukin 6.