Table 1. Clinical characteristic of acute lymphoblastic leukemia patients who donated cell samples for in vitro analysis.
| pt # | Sex/Age (yrs) | FAB category | Sample | WBC counts (109/L) | Blast (%) | Genetic abnormalities | Treatment status at sample collection |
|---|---|---|---|---|---|---|---|
| 1 |
F/8 |
ALL-L2 |
PB |
44 |
73 |
BCR/ABL t(9;22)MLL t(11q23)TEL/ AML1t(12;21) negative |
untreated |
| 2 |
F/3.5 |
ALL-L2 |
BM |
16.5 |
96 |
BCR/ABL t(9;22) |
untreated |
| 3 |
M/11 |
ALL-L2 |
PB |
216.45 |
90.1 |
BCR/ABL t(9;22)72%/ MLL negative |
untreated |
| 4 |
M/3 |
ALL-L1 |
PB |
110 |
90 |
BCR/ABL t(9;22); MLL t(11q23)TEL/ AML1t(12;21) negative |
untreated |
| 5 |
F/6 |
ALL |
PB |
4.7 |
75 |
TEL/AML1 t(12;21)40% |
untreated |
| 6 |
M/15 |
ALL |
PB |
61.27 |
92.5 |
none detected |
untreated |
| 7 |
F/42 |
ALL |
PB |
1.27 |
8 |
FISH BCR-ABL(-) |
untreated |
| 8 |
M/11 |
ALL-L2 |
BM |
99.12 |
58 |
none detected |
untreated |
| 9 | M/15 | ALL-L2 | BM | 210 | 84 | none detected | untreated |
F: female; M: male; PB: peripheral blood; BM: bone marrow; FISH: fluorescent in situ hybridization.