Table 4. Concentrations of metformin and rosiglitazone that can decrease leukemic cells by 5% in 3 d.
| Sample | Metformin (µM) | Rosiglitazone (µM) | |
|---|---|---|---|
| Cell lines |
Reh |
70.6 |
11.3 |
| Nalm-6 |
32.1 |
4.15 |
|
| Raji |
45.7 |
11.5 |
|
| CCRF-CEM |
60 |
36.6 |
|
| |
Median |
52.85 |
11.40 |
| |
Mean |
52.1 |
15.89 |
| Patient Samples |
Patient 1 |
25.2 |
27.8 |
| Patient 2 |
61.8 |
40.1 |
|
| Patient 4 |
13.1 |
2.68 |
|
| Patient 8 |
31.1 |
3.29 |
|
| Patient 9 |
10.8 |
8.16 |
|
| |
Median |
25.2 |
8.16 |
| |
Mean |
28.4 |
16.41 |
| Mann-Whitney U test (Cell Lines vs. Patient Samples) | p = 0.111 | p = 0.730 | |