Figure 2. Increased SREBP1 expression in atypical hyperplasia. (A) IHC staining was conducted with anti-SREBP1 antibody on endometrial tissues derived from normal, hyperplasia without atypia and atypical hyperplasia. Secretory, proliferative and post-menopausal normal endometrial tissues were stained. (B) Boxplot of IHC staining score for SREBP1 in whole cell, cytoplasm and nucleus in normal hyperplasic, and cancerous tissues in all specimens recruited to this study as indicated. Statistical analysis of SREBP1 expression was performed showing the p-value for the difference among the experimental groups (bottom panels).