Table 3A.
Effect of anthelminthic treatment on HIV-1 load
| A. Six weeks post-treatment | |||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Group | Mean (SE) log10 HIV load at baselinea |
Mean (SE) log10 HIV load at six weeks post-treatment |
Crude mean difference (95% CI) |
Adjusted mean difference (95% CI)b |
p | ||
| Placebo | Albendazole | Placebo | Albendazole | ||||
|
| |||||||
| All women | 4.21 (0.11) | 3.92 (0.10) | 4.26 (0.10) | 3.85 (0.09) | −0.40 (−0.68, −0.13) | −0.17 (−0.36, 0.01) | 0.07 |
| Hookworm infected | 4.32 (0.18) | 3.99 (0.18) | 4.18 (0.16) | 3.85 (0.16) | −0.33 (−0.77, 0.11) | −0.12 (−0.46, 0.22) | 0.44c |
| Hookworm uninfected | 4.13 (0.13) | 3.88 (0.13) | 4.31 (0.13) | 3.85 (0.12) | −0.46 (−0.81, −0.10) | −0.22 (−0.44, −0.01) | |
|
| |||||||
| Placebo | Praziquantel | Placebo | Praziquantel | ||||
|
| |||||||
| All women | 4.08 (0.10) | 4.05 (0.11) | 4.06 (0.09) | 4.05 (0.11) | −0.01 (−0.29, 0.27) | 0.01 (−0.18, 0.20) | 0.94 |
| S. mansoni infected | 3.89 (0.22) | 4.17 (0.27) | 3.80 (0.22) | 4.12 (0.27) | 0.32 (−0.38, 1.02) | 0.07 (−0.27, 0.41) | 0.56c |
| S. mansoni uninfected | 4.11 (0.11) | 4.02 (0.12) | 4.11 (0.10) | 4.03 (0.12) | −0.08 (−0.39, 0.23) | −0.02 (−0.24, 0.20) | |
a
For those with viral load measured at six weeks post-treatment
b
For effect of albendazole treatment, results were adjusted for baseline viral load, baseline malaria parasitaemia and viral load assay used at six weeks; for effect of praziquantel treatment, results were adjusted for baseline viral load
c
Interaction p-value
SE=standard error;CI=confidence interval