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. Author manuscript; available in PMC: 2013 May 15.
Published in final edited form as: Int J Parasitol. 2012 Apr 19;42(6):575–582. doi: 10.1016/j.ijpara.2012.03.006

Fig. 2.

Fig. 2

Methodologies employed for functional analysis of erythrocyte determinants of Plasmodium invasion and growth. Various experimental procedures have been employed to target both cytoplasmic and surface exposed erythrocyte determinants of invasion. Experiments employing naturally occurring mutants, biochemical approaches, chemical biological approaches and transgenic approaches have been used to identify and confirm the role of host determinants of invasion via absence, interference, ectopic expression, and over-expression. shRNA KD, small hairpin RNA knock-down.