Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Molecular features of colorectal cancer by analysis of DNA from HE-stained tissue in two U.S. nationwide prospective cohort studies, the Nurses’ Health Study and the Health Professionals Follow-up Study.
| Molecular features | N | |
|---|---|---|
| KRAS | 1314 | |
| Codon 12 or 13 mutation | 470 (36%) | |
| Wild-type | 844 (64%) | |
| BRAF | 1313 | |
| Codon 600 mutation | 186 (14%) | |
| Wild-type | 1127 (86%) | |
| MSI | 1293 | |
| MSI-high | 197 (15%) | |
| MSS/MSI-low | 1096 (85%) | |
HE, hematoxylin and eosin; MSI, microsatellite instability; MSS, microsatellite stable.
