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. 2012 Jun 26;7(6):e39791. doi: 10.1371/journal.pone.0039791

Figure 3. Tissue-specific effects of prenatal stress on DNA methylation of the HSD11B2 promoter and exon 1.

Figure 3

Average (mean ± SEM) % DNA methylation at 38 CpG sites in the HSD11B2 promoter and exon 1 in (A) fetal hypothalamus, (B) fetal cortex, and (C) placenta of control offspring and offspring exposed to prenatal stress. Location of Sp1 and NF-κB transcription factor binding sites indicated, as well as the transcription start site (TSS) and ATG start codon. (n = 4/group run in duplicate; *p<0.05).