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. 2012 Jun 26;7(6):e39696. doi: 10.1371/journal.pone.0039696

Figure 3. Sodium butyrate (NaB) abolished the SSZ-induced inhibition of extinction of morphine withdrawal-associated aversive memory.

Figure 3

(A) Timeline of experiment procedure. (B) Systemic pretreatment with NaB abolished the SSZ-induced inhibition of extinction of morphine withdrawal-associated aversive memory. The data are expressed as the mean ± SEM CPA score in seconds (time spent in the drug-paired chamber minus time spent in the saline-paired chamber) during the CPA tests. *p<0.01, different from control group (0 mM SSZ treatment group). Sal, saline; SSZ, sulfasalazine; Pre-C, pre-conditioning; Post-C, post-conditioning; Post-T, post-treatment.