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(A), (B) and (C) represent mPEG-rCU-1, mPEG-rCU-2 and mPEG-rCU-3.The magnification is 100000×, scale bar: 200 nm. a, b and c may correspond to PEGylated tetrameric uricase, PEGylated aggregated uricase, and cross-linked conjugates induced by PEG diol, respectively.
