Table 1. COPs are overexpressed and implicated in the pathophysiology of a number of cancer lineages.
| Tumor Type | COPA | COPB1 | COPB2 | COPG1 | COPG2 | COPD | COPE | COPZ1 | COPZ2 |
| Bladder | 10−7 | ||||||||
| Pancreatic | |||||||||
| Cervical | |||||||||
| Breast | 10−11 | 10−9 | 10−9 | 10−20 | |||||
| Liver | |||||||||
| HN | |||||||||
| Lymphoma | |||||||||
| Prostate | 10−9 | 10−7 | 10−6 | ||||||
| Sarcoma | 10−11 | ||||||||
| Lung | |||||||||
| Brain, CNS | |||||||||
| Colorectal | 10−17 | 10−10 | 10−8 | 10−13 | |||||
| Ovarian | 10−8 | 10−15 | |||||||
| Kidney |
Aberrations with P≤10–6 are indicated. Data are derived from a reanalysis of Bittner Multicancer Dataset (www.oncomine.org). HN, Head and Neck; CNS, Central Nervous System.