Table 3.

Hazard ratios (95 % CI) for all-cause mortality through 2005 and 5-year breast cancer mortality according to diabetes diagnosis, stratified by breast cancer risk factors among women diagnosed with breast cancer in 1996–1997, Long Island Breast Cancer Study Project

	All cause survival						Breast cancer 5-year survival
	Diabetes		No diabetes		HRa	95 % CI	Diabetes		No diabetes		HRa	95 % CI
	Deaths	Total pop	Deaths	Total pop			Deaths	Total pop	Deaths	Total pop
All women	49	121	246	1,326	1.65	1.18–2.29	14	121	90	1,326	1.17	0.63–2.19
Menopausal status
Premenopausal women	4	12	63	456	1.30	0.43–3.89	3	12	32	457	1.76	0.48–6.49
Postmenopausal women	45	109	183	870	1.74	1.23–2.45	11	109	58	870	1.12	0.56–2.25
Age at breast cancer diagnosis
<65 years	15	50	123	895	1.47	0.81–2.68	5	50	62	895	0.78	0.28–2.16
≥65 years	34	71	123	431	1.63	1.09–2.43	9	71	28	431	1.60	0.72–3.54
BMI (kg/m2)
BMI >18.5 to <30	19	67	186	1,060	1.20	0.73–1.99	7	67	64	1,060	1.49	0.64–3.48
BMI ≥30	30	54	60	263	2.49	1.58–3.93	7	54	26	263	1.22	0.51–2.91
Ever regular lifetime physical activityb
None	24	52	96	373	1.55	0.95–2.53	8	52	36	373	1.22	0.51–2.88
Any	25	68	149	946	1.76	1.12–2.78	6	68	54	946	1.04	0.40–2.72
Ever regular alcohol drinker
Never drinker	27	69	98	495	1.68	1.07–2.63	6	69	38	495	0.73	0.29–1.82
Ever drinker	22	52	148	831	1.61	0.98–2.64	8	52	52	831	2.14	0.90–5.10
Average daily caloric intakec
<1,275.1 KCAL	26	69	118	665	1.60	1.01–2.53	4	69	42	665	0.73	0.24–2.15
≥1,275.1 KCAL	18	43	119	630	1.81	1.07–3.08	8	43	45	630	2.05	0.89–4.69
Ever take hormone replacementd
No	38	88	141	586	1.70	1.17–2.48	9	88	46	586	1.05	0.49–2.24
Yes	6	20	45	299	1.86	0.77–4.50	1	20	12	299	1.01	0.13–7.92
Estrogen–Progesterone Receptor Statuse
ER−PR−	12	17	54	187	1.53	0.76–3.10	5	17	32	187	0.79	0.27–2.31
ER−PR + breast cancer	2	6	13	44	0.69	0.11–4.22	1	6	4	44	0.32	0.01–12.5
ER + PR− breast cancer	5	12	33	127	2.33	0.83–6.55	2	12	14	127	1.82	0.36–9.25
ER + PR+	21	52	87	510	1.70	1.02–2.85	4	52	22	510	1.32	0.41–4.24
Estrogen Receptor Statuse
ER−	14	23	67	231	1.48	0.79–2.77	6	23	36	231	0.83	0.32–2.14
ER+	26	64	120	637	1.74	1.11–2.74	6	64	36	637	1.44	0.56–3.67)
Progesterone Receptor Statuse
PR−	17	29	87	314	1.93	1.10–3.37	7	29	46	314	1.25	0.54–2.93
PR+	23	58	100	554	1.64	1.01–2.85	5	58	26	554	1.35	0.48–3.81

^aAdjusted for menopausal status, race (white, other), obesity (BMI <30, BMI ≥30), and history of myocardial infarction

^b8 missing responses for any lifetime physical activity

^c40 missing responses for average daily caloric intake

^dAmong postmenopausal women

^eNot all breast cancer cases had data for receptor status (n = 955 with receptor status)