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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Int J Obes (Lond). 2012 Feb 7;37(2):272–278. doi: 10.1038/ijo.2012.16

Figure 1.

Figure 1

Quadratic surface plots for cumulative food intake at 1, 4, and 20 hr after IP administrations of doses of Nal or Ex-4 alone and the 2 drugs combined. Data are presented as percentage of the corresponding hourly saline injection intake. The bottom tips of all 3 surface plots do not extend to the front junction of the Ex-4 and Nal axis suggesting additive effects on food intake suppression after treatments of Nal + Ex-4 at all time points measured. These additive effects are confirmed by response surface regression (see Experiment 1 Results).