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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2012 Jul 1;60(3):225–233. doi: 10.1097/QAI.0b013e3182515730

Table 4.

Resistance by UDPS in pre-HAART infant plasma

ID min # of 454 reads NVP resistance mutations detected by UDPS1
NRTI2
total % reistance # of sites with NVP resistance3 # of sites NVP + NRTI resistance3 months of follow-up time of VF
K101
K103
V106
Y181
G190
F227
M184
E N S T A M C A E T C 1
7 11134 0.21% bd bd bd bd bd bd bd bd bd bd bd 0.21% 1 1 21 month 6
9 8598 bd bd bd bd bd bd bd bd bd bd bd 0.13% 0.13%* 0 1 6 month 3
11 12999 bd bd bd bd bd bd bd bd bd bd 0.07% bd 0.07% 1 1 21 month 21
17 11029 bd bd bd bd bd bd bd bd bd bd bd 0.23% 0.23%* 0 1 3 month 3
19 6203 0.20% bd bd bd bd bd bd 3.76% bd bd bd bd 3.96% 2 2 3 month 3
22 9529 bd 49.90% bd 0.32% bd bd 0.49% 0.34% bd bd bd bd 51.05% 3 3 12 month 6
24 4212 bd 10.62% bd 0.80% 9.97% 0.19% bd 0.65% bd bd bd bd 22.24% 3 3 12 month 9
2 5374 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 24 int
3 15058 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 12 nf
4 14402 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 6 nf
8 10382 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 21 nf
12 14318 bd 99.83% 0.18% bd bd bd bd bd bd bd bd bd 100.01% 1 1 3 nf
14 4497 bd bd bd bd bd bd bd 99.95% bd 0.06% bd bd 100.01% 1 1 3 nf
15 13633 bd 99.71% 0.13% bd bd bd bd bd bd bd bd bd 99.83% 1 1 3 nf
18 15305 bd bd bd bd bd bd bd bd 0.64% bd bd bd 0.64% 1 1 12 nf
20 14478 bd 0.18% bd bd bd bd 0.36% bd bd bd bd bd 0.54% 2 2 3 nf
28 13964 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 3 nf
29 4923 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 9 nf
30 7783 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 6 nf
32 13646 bd bd bd bd bd bd bd bd bd bd bd bd 0% 0 0 3 nf

bd = below detection, VF = viral failure, int = intermittent viremia, nf = no failure

1

NVP resistance mutations assayed by UDPS with no detectable resistance in any samples are not included in the table: L100I, K101P, V179F, Y181I/S/V, Y188C/H/L, G190C/Q/S/V

2

NRTI resistance mutations assayed by UDPS with no detectable resistance in any samples are not included in table: Q151M, M184V, T215F/Y

3

Changes to different amino acids at the same position were counted as a single site of resistance

*

For these cases, resistance would be 0% if NRTI sites were excluded.