Table 2.
RT-PCR results from Control v MC lung and CNS selected tissues
| Anatomical region and target gene | Controls | Mexico City | p value |
|---|---|---|---|
| LUNG COX2 | 15.9 ± 6.7 × 106 | 42.3 ± 7.4 × 106 | p=0.01 |
| FRONTAL COX2 | 2.6 ± 0.4 × 105 | 5.0 ± 0.7 × 105 | p=0.008 |
| FRONTAL IL1β | 0.6 ± 0.2 × 104 | 6.2 ± 1.3 × 104 | p=0.0002 |
| OB COX2 | 6.3 ± 1.4 × 104 | 7.9 ± 8.7 × 105 | p=0.005 |
| OB IL1β | 2.5 ± 0.95 × 104 | 4.08 ± 12.3 × 105 | p=0.08 |
| FRONTAL L1G1 | 0.18 ± 0.16 | 2.4 ± 7.7 | p=0.06 |
| FRONTAL OGG1 | 1.91 ± 1.22 × 10-3 | 1.297 ± 4.459 | p=0.06 |
| FRONTAL XPA | 1.872 ± 1.365 × 10-3 | 3.611 ± 9.847 × 10-2 | p=0.22 |
| OB L1G1 | 3.285 ± 1.316 × 10-2 | 0.5557 ± 1.357 | p=0.34 |
| OB OGG1 | 5.547 ± 1.986 × 10-3 | 2.789 ± 4.771 × 10-2 | p=0.61 |
| OB XPA | 3.411 ± 1.919 × 10-3 | 2.868 ± 1.460 × 10-3 | p=0.42 |
Abbreviations: OB, olfactory bulb; RT-PCR, real-time polymerase chain reaction. The amount of COX2, IL-1β, L1G1, OGG1, and XPA cDNA in each sample was normalized to the amount of GAPDH cDNA, yielding an index (molecules per attomol GAPDH rRNA) proportional to the relative abundance of each mRNA in each sample. Values are expressed as molecules/attomol GAPDH. Values are mean ± SD