Table 5.
Multivariate analysis of factors that influence overall survival in patients with renal cell carcinoma
| Variable | Categories | N | H.R. | 95% CI for H.R.
|
p-value | |
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
|
| ||||||
| Age at diagnosis of RCC | <60 | 3,799 | 0.54 | 0.49 | 0.58 | <0.001 |
| ≥60 yrs | 3,156 | - | ||||
| Gender | Male | 2,593 | 1.22 | 1.12 | 1.33 | <0.001 |
| Female | 4,362 | 1.00 | ||||
| Race | Others | 5,858 | 1.23 | 1.10 | 1.37 | <0.001 |
| Whites | 1,097 | 1.00 | ||||
| Marital status | Othersa | 4,710 | 1.34 | 1.23 | 1.46 | <0.001 |
| Married | 2,245 | 1.00 | ||||
| Summary stage | Regional or Distant | 4,739 | 2.94 | 2.68 | 3.22 | <0.001 |
| Localized | 2,216 | 1.00 | ||||
| Grade | PD or UD | 4,592 | 1.83 | 1.68 | 1.99 | <0.001 |
| WD or MD | 6,718 | - | ||||
| Size of tumor | ≤5cm | 3,586 | 0.69 | 0.63 | 0.75 | <0.001 |
| >5cm | 3,369 | - | ||||
| Radiation therapy | No | 302 | 0.39 | 0.34 | 0.45 | <0.001 |
| Yes | 6,653 | - | ||||
| Laterality | Unilateral | 6,952 | 0.31 | 0.14 | 0.71 | 0.001 |
| Bilateral | 6 | |||||
Hazards ratio (H.R.), confidence interval (CI), only primary cancer (OPC), second primary cancer (SPC), well differentiated (WD), moderately differentiated (MD), poorly differentiated (PD)
Variables not in the final model: Sequence of RCC (OPC vs. SPC).