. Author manuscript; available in PMC: 2014 Apr 1.

Published in final edited form as: Am J Clin Oncol. 2013 Apr;36(2):132–142. doi: 10.1097/COC.0b013e3182438ddf

Table 7.

Multivariate analysis of factors influencing overall survival in renal cell carcinoma patients with second primary cancers

Variable	Categories	H.R.	95% CI for H.R.		p-value
Variable	Categories	H.R.	Lower	Upper	p-value

Age at diagnosis of SPC	<60 years	0.46	0.27	0.82	0.006
Age at diagnosis of SPC	≥60 years	-
Received radiation	No	0.16	0.07	0.38	0.006
Received radiation	Yes	-
Months elapsed between FPC and SPC	0–11 months	2.10	1.40	3.20	<0.001
Months elapsed between FPC and SPC	≥12 months	-

Hazards ratio (H.R.), confidence interval (CI), only primary cancer (OPC), second primary cancer (SPC), well differentiated (WD), moderately differentiated (MD), poorly differentiated (PD) and undifferentiated (UD).

Including divorced, widowed, separated and never married (single) individuals Variables not included in the model: Age at diagnosis of SPC (<60 years vs. ≥60 years), Race (Whites vs. others), grade of tumor (well and moderately differentiated vs. undifferentiated), size of tumor (≤5cm vs. >5cm), Radiation sequence with surgery (given vs. not given), gender (male vs. female), radiation or radioisotope therapy (given vs. none) and laterality (right vs. left origin of the primary renal tumor).