Figure 6.

Quantitative reverse transcriptase polymerase chain analysis for days 1, 7, 14, and 21 for early osteoblastic marker ALP. Values are normalized to day one control large bead inner. All groups are cultured in osteogenic media. On day 21 ALP expression levels are significantly higher in bioreactor large bead inner cells than all other groups. The symbols (*, #) indicate statistical significance from all other groups within a timepoint (p < 0.05). Groups with symbol * or # are statistically different from all groups except those groups with the same symbol. Groups with the same symbol are statistically similar to each other.